ABSTRACT
As COVID-19 vaccines have been distributed worldwide, the number of infection and death cases vary depending on the vaccination route. Therefore, computing optimal measures that will increase the vaccination effect are crucial. In this paper, we propose an Epidemic Vulnerability Index (EVI) that quantitatively evaluates the risk of COVID-19 based on clinical and social statistical feature analysis of the subject. Utilizing EVI, we investigate the optimal vaccine distribution route with a heuristic approach in order to maximize the vaccine distribution effect. Our main criterias of determining vaccination effect were set with mortality and infection rate, thus EVI was designed to effectively minimize those critical factors. We conduct vaccine distribution simulations with nine different scenarios among multiple Agent-Based Models that were constructed with real-world COVID-19 patients’ statistical data. Our result shows that vaccine distribution through EVI has an average of 5.0% lower in infection cases, 9.4% lower result in death cases, and 3.5% lower in death rates than other distribution methods. © 2021, Springer Nature Switzerland AG.